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Nie Huan
Publisher:马文君  Time2016-12-23 View:122

Nie Huan

PhD associate professor


Research Area:cancer glycomic, metabonomic and chemistrybiology

Assistant Dean of School and the vice director of the Center of Biomedical Basic Research.

His research interest is focused on the cancer glycomic, metabonomic and chemistrybiology. Due to the fact that the change of the glycan and small molecule metabolites are closely related to the occurrence and development of cancer, Dr Nie studies the relation between cancer and the varieties of glycan and metabolites. It is expected to be used in clinical as a noninvasive, rapid, and convenient high-throughput detection method. On the other hand, the research result will offer the target molecule for cancer diagnose and healing to build specific target tracking.

Dr Nie leads some national projects including National Natural Science Foundation of China (NSFC) (30700987, 81171945, C050204), forty-fifth Postdoctoral Science Foundation of China(20090451003)Principal Investigator, Development Project of Outstanding Young Teachers in Harbin Institute of Technology Grants for Principal(HITQNJS.2007.026).


  1. Narla SN, Pinnamaneni P, Nie H, Li Y ,Sun XL*. BSA-boronic acid conjugate as lectin mimetics. Biochem Biophys Res Commun.2014; J443(2):562-7.

  2. Xia Liu, Huan Nie, Yubao Zhang, Yuanfei Yao, Alaiyi Maitikabili, Youpeng Qu, Shuliang Shi, Cuiying Chen,* and Yu Li*, Cell Surface-Specific N-glycan Profiling for Breast Carcinoma by DSA-FACE, Plos One, 2013; 8 (8): e72704. Co-first author

  3. Nie Huan, Yao Yuanfei, Ding Ning, Liu Xia, Qu Youpeng, Li Yu*The N-Glycomic research on the Serum Biomarkers of Breast Cancer. Clinical and Experimental Pharmacoogy and Physiology. 2013; (40), Issue Supplement s1, 16

  4. Xia Liu, Huan Nie, Xuelong Sun, Yu Li*,The Study on the Alteration Mechanism of Specific N-glycan for Hepatocellular Carcinoma. 9th Annual Midwest Carbohydrate and Glycobiology Symposium.2013,10, America, Toledo,23,

  5. Huan Nie, Yu Li* ,Xue-Long Sun. Recent Advances in Sialic Acid-Focused Glycomics. Journal of Proteomics. 2012; 75(11):3098-3112,

  6. Satya Nandana Narla, Huan Nie, Yu Li*, Xue-Long Sun*. Recent Advances in the Synthesis and Biomedical Applications of Chain-End Functionalized Glycopolymers. Journal of Carbohydrate Chemistry, 2012; 31(2):67-92,

  7. Ding N, Nie H, Sun X, Sun W, Qu Y, Liu X, Yao Y, Liang X, Chen CC, Li Y*. Human Serum N-Glycan Profiles Are Age and Sex Dependent. Age Ageing. 2011; 40(5):568-75. Co-first author

  8. Huan Nie,Ding ning,Sun wei,Yu Youtao ,Yu Yan,Zhang Yubao ,Qu Youpeng, Wang Shan, Li Yu*. N-Glycomic Changes in Serum for the Discovery of Potential Biomarkers of Breast Cancer. 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology

  9. Peng J, Yang L, Yang F, Yang J, Yan Y, Nie H, Zhang X, Xiong Z, Jiang Y, Cheng F, Xu X, Chen S, Sun L, Li W, Shen Y, Shao Z, Liang X, Xu J, Jin Q*. Characterization of ST-4821 complex, a unique Neisseria meningitidis clone. Genomics. 2008; 91(1):78-87.

  10. Yang J, Nie H, Chen L, Zhang X, Yang F, Xu X, Zhu Y, Yu J, Jin Q*.Revisiting the Molecular Evolutionary History of Shigella spp. J Mol Evol. 2007; 64(1):71-9 Co-first author

  11. Nie H, Yang F, Zhang X, Yang J, Chen L, Wang J, Xiong Z, Peng J, Sun L, Dong J, Xue Y, Xu X, Chen S, Yao Z, Shen Y, Jin Q*.Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a. BMC Genomics. 2006; 7:173.

  12. Xiong Z, Tang X, Yang F, Zhang X, Yang J, Chen L, Nie H, Yan Y, Jiang Y, Wang J, Xue Y, Xu X, Zhu Y, Dong J, An L, Wang X, Jin Q*.Comparison of the virulence plasmid genomes of two strains of Shigella which lost the ability to bind Congo red.Sci China C Life Sci. 2006; 49(2):141-8.

  13. Liu W, Nie H, Wang S, Li X, He Z, Han C, Wang J, Chen X, Li L, Yu J*. Mapping a resistance gene in wheat cultivar Yangfu 9311 to yellow mosaic virus, using microsatellite markers. Theor Appl Genet. 2005; 111(4):651-7.

  • Wei-Hua LIU, Huan NIE, Zhen-Tian HE, Xiu-Lan CHEN, Yue-Peng HAN, Jin-Rong WANG, Xin LI, Cheng-Gui HAN and Jia-Lin YU*.Mapping of a Wheat Resistance Gene to Yellow Mosaic Disease by Amplified Fragment Length Polymorphism and Simple Sequence Repeat Markers. Journal of Integrative Plant Biology 2005; 47 (9): 1133-1139

  1. Yang F, Yang J, Zhang X, Chen L, Jiang Y, Yan Y, Tang X, Wang J, Xiong Z, Dong J, Xue Y, Zhu Y, Xu X, Sun L, Chen S, Nie H, Peng J, Xu J, Wang Y, Yuan Z, Wen Y, Yao Z, Shen Y, Qiang B, Hou Y, Yu J, Jin Q*.Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res. 2005; 33(19):6445-58.

  2. Jiang Y, Yang F, Zhang X, Yang J, Chen L, Yan Y, Nie H, Xiong Z, Wang J, Dong J, Xue Y, Xu X, Zhu Y, Chen S, Jin Q*.The complete sequence and analysis of the large virulence plasmid pSS of Shigella sonnei. Plasmid. 2005; 54(2):149-59.